(−)-Epigallocatechin-3-gallate derivatives combined with cisplatin exhibit synergistic inhibitory effects on non-small-cell lung cancer cells

(−)-Epigallocatechin-3-gallate derivatives combined with cisplatin exhibit synergistic inhibitory effects on non-small-cell lung cancer cells

Abstract Background Non-small-cell lung cancer (NSCLC) is the leading cause of cancer-related death worldwide. The inhibition of epidermal growth factor receptor (EGFR) signaling by tyrosine kinase inhibitors or monoclonal antibodies plays a key role in NSCLC treatment. Unfortunately, these treatmen...

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Bibliographic Details
Main Authors: Jing Wang, Peiyuan Sun, Qi Wang, Pan Zhang, Yuna Wang, Chengting Zi, Xuanjun Wang, Jun Sheng
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Cancer Cell International
Subjects:
NSCLC
Synthesis
Cisplatin
EGCG derivatives
EGFR
Online Access:http://link.springer.com/article/10.1186/s12935-019-0981-0

Internet

http://link.springer.com/article/10.1186/s12935-019-0981-0

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