Asynchronous replication, mono-allelic expression, and long range Cis-effects of ASAR6.
Mammalian chromosomes initiate DNA replication at multiple sites along their length during each S phase following a temporal replication program. The majority of genes on homologous chromosomes replicate synchronously. However, mono-allelically expressed genes such as imprinted genes, allelically ex...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-04-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC3617217?pdf=render |