Asynchronous replication, mono-allelic expression, and long range Cis-effects of ASAR6.

Mammalian chromosomes initiate DNA replication at multiple sites along their length during each S phase following a temporal replication program. The majority of genes on homologous chromosomes replicate synchronously. However, mono-allelically expressed genes such as imprinted genes, allelically ex...

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Bibliographic Details
Main Authors: Nathan Donley, Eric P Stoffregen, Leslie Smith, Christina Montagna, Mathew J Thayer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-04-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3617217?pdf=render