A novel and cost-effective ex vivo orthotopic model for the study of human breast cancer in mouse mammary gland organ culture

A novel and cost-effective ex vivo orthotopic model for the study of human breast cancer in mouse mammary gland organ culture

Mouse mammary organ culture (MMOC) is used to evaluate the efficacy of chemopreventive agents against the development of carcinogen-induced preneoplastic lesions and is highly correlative to in vivo carcinogenesis models. Here, we developed a new ex vivo MMOC model, by introducing human breast cance...

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Bibliographic Details
Main Authors: Akash Gupta, Geetanjali Gupta, Rajeshwari R. Mehta, David Z. Ivancic, Rashidra R. Walker, Jankiben R. Patel, Karen M. Gallegos, A. Michael Davidson, Seema A. Khan, Rajendra G. Mehta, Syreeta L. Tilghman
Format: Article
Language:English
Published: The Company of Biologists 2020-05-01
Series:Biology Open
Subjects:
breast cancer model
orthotopic model
organ culture
mammary gland
Online Access:http://bio.biologists.org/content/9/5/bio051649

Internet

http://bio.biologists.org/content/9/5/bio051649

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