Characterization of a human induced Pluripotent Stem (iPS) cell line (INCABRi002-A) derived from a primary myelofibrosis patient harboring the 5-bp insertion in CALR and the p.W146X mutation in TP53

Characterization of a human induced Pluripotent Stem (iPS) cell line (INCABRi002-A) derived from a primary myelofibrosis patient harboring the 5-bp insertion in CALR and the p.W146X mutation in TP53

Primary myelofibrosis (PMF) is a hematological malignancy characterized by activation of the JAK/STAT pathway and risk of leukemic transformation. In this study, we generated an induced Pluripotent Stem (iPS) cell line derived from a 65-year old male PMF patient carrying the 5-pb insertion in the CA...

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Main Authors: Cintia E. Gomez Limia, Sylvie Devalle, Marcelo Reis, Jaroslaw Sochacki, Rodrigo Madeiro da Costa, Mariana D'Andrea, Telma Padilha, Ilana R. Zalcberg, Cristiana Solza, Adelmo Daumas, Stevens Rehen, Martín H. Bonamino, Bárbara Monte-Mór
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506118302344

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http://www.sciencedirect.com/science/article/pii/S1873506118302344

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