Effects of methotrexate upon inflammatory parameters induced by carrageenan in the mouse model of pleurisy
Background: The model of pleurisy induced by carrageenan exhibits a biphasic response (4 and 48 h) and permits the quantification of exudate, cell migration and certain enzymes such as myeloperoxidase (MPO) and adenosine-deaminase (ADA) that are markers of activated leukocytes.
Main Authors: | Eduardo Monguilhott Dalmarco, Tânia Silvia Fröde, Yara Santos Medeiros |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2002-01-01
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Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1080/09629350210000015700 |
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