Effects of methotrexate upon inflammatory parameters induced by carrageenan in the mouse model of pleurisy

Background: The model of pleurisy induced by carrageenan exhibits a biphasic response (4 and 48 h) and permits the quantification of exudate, cell migration and certain enzymes such as myeloperoxidase (MPO) and adenosine-deaminase (ADA) that are markers of activated leukocytes.

Bibliographic Details
Main Authors: Eduardo Monguilhott Dalmarco, Tânia Silvia Fröde, Yara Santos Medeiros
Format: Article
Language:English
Published: Hindawi Limited 2002-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1080/09629350210000015700