Enzymatic degradation of PrPSc by a protease secreted from Aeropyrum pernix K1.

Enzymatic degradation of PrPSc by a protease secreted from Aeropyrum pernix K1.

BACKGROUND: An R30 fraction from the growth medium of Aeropyrum pernix was analyzed for the protease that can digest the pathological prion protein isoform (PrP(Sc)) from different species (human, bovine, deer and mouse). METHODOLOGY/PRINCIPAL FINDINGS: Degradation of the PrP(Sc) isoform by the R30...

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Bibliographic Details
Main Authors: Marko Snajder, Tanja Vilfan, Maja Cernilec, Ruth Rupreht, Mara Popović, Polona Juntes, Vladka Čurin Serbec, Nataša Poklar Ulrih
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3386259?pdf=render

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http://europepmc.org/articles/PMC3386259?pdf=render

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