Silencing Pin1 Suppresses the Expression and Bioactivity of MMP-9 through NF-κB in Colorectal Carcinoma SW480 Cells

Silencing Pin1 Suppresses the Expression and Bioactivity of MMP-9 through NF-κB in Colorectal Carcinoma SW480 Cells

OBJECTIVE To examine the effect of Pin1 on the expression and bioactivity of MMP-9 through NF-κB in human colorectal carcinoma SW480 cells.METHODS The eukaryotic expression vector of RNA interfering (shRNA) with the Pin1 gene (pGenesil-1-PIN1) was constructed in our previous experiments and was co...

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Bibliographic Details
Main Author: Li-yuan QIN, Mei-ning LI, Wen-juan REN
Format: Article
Language:English
Published: China Anti-Cancer Association 2010-02-01
Series:Cancer Biology & Medicine
Subjects:
colorectal cancer
Pin1
RNAi
MMP-9
NF-κB.
Online Access:http://www.cancerbiomed.org/index.php/cocr/article/view/150

Internet

http://www.cancerbiomed.org/index.php/cocr/article/view/150

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