Pretreatment with Group II Metabotropic Glutamate Receptor Agonist LY379268 Protects Neonatal Rat Brains from Oxidative Stress in an Experimental Model of Birth Asphyxia

Pretreatment with Group II Metabotropic Glutamate Receptor Agonist LY379268 Protects Neonatal Rat Brains from Oxidative Stress in an Experimental Model of Birth Asphyxia

Hypoxia-ischemia (H-I) at the time of birth may cause neonatal death or lead to persistent brain damage. The search for an effective treatment of asphyxiated infants has not resulted in an effective therapy, and hypothermia remains the only available therapeutic strategy. Among possible experimental...

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Bibliographic Details
Main Authors: Ewelina Bratek, Apolonia Ziembowicz, Elzbieta Salinska
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:Brain Sciences
Subjects:
hypoxia-ischemia
birth asphyxia
group II metabotropic glutamate receptors
LY379268
neuroprotection
oxidative stress
Online Access:http://www.mdpi.com/2076-3425/8/3/48

Internet

http://www.mdpi.com/2076-3425/8/3/48

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