Plasma neurofilament light chain is associated with cognitive decline in non-dementia older adults

Abstract Neurofilament light chain (NfL) has been associated with cognitive status in multiple neurodegenerative conditions. Studies about plasma NfL and cognitive decline in older adults are still limited. 504 older adults (median age 75 years) who expressed memory complaints were selected from the...

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Bibliographic Details
Main Authors: Lingxiao He, John E. Morley, Geetika Aggarwal, Andrew D. Nguyen, Bruno Vellas, Philipe de Souto Barreto, the MAPT/DSA Group
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-91038-0