The "Two-Faced" Effects of Reactive Oxygen Species and the Lipid Peroxidation Product 4-Hydroxynonenal in the Hallmarks of Cancer

Reacytive Oxygen Species (ROS) have long been considered to be involved in the initiation, progression and metastasis of cancer. However, accumulating evidence points to the benefical role of ROS. Moreover, ROS production, leading to apoptosis, is the mechanism by which many chemotherapeutic agents...

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Bibliographic Details
Main Authors: Stefania Pizzimenti, Cristina Toaldo, Piergiorgio Pettazzoni, Mario U. Dianzani, Giuseppina Barrera
Format: Article
Language:English
Published: MDPI AG 2010-03-01
Series:Cancers
Subjects:
ROS
Online Access:http://www.mdpi.com/2072-6694/2/2/338/