Anthrax Lethal Toxin-Induced Gene Expression Changes in Mouse Lung

Anthrax Lethal Toxin-Induced Gene Expression Changes in Mouse Lung

A major virulence factor of Bacillus anthracis is the anthrax Lethal Toxin (LeTx), a bipartite toxin composed of Protective Antigen and Lethal Factor. Systemic administration of LeTx to laboratory animals leads to death associated with vascular leakage and pulmonary edema. In this study, we investig...

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Bibliographic Details
Main Authors: A. Darise Farris, Judith A. James, Igor Dozmorov, Mark Barton Frank, Michael Centola, Melissa Nguyen, Charles O’Connor Fullenwider, Philip M. Cox, Eric K. Dumas
Format: Article
Language:English
Published: MDPI AG 2011-09-01
Series:Toxins
Subjects:
Lethal Toxin
lung
gene expression
Online Access:http://www.mdpi.com/2072-6651/3/9/1111/

Internet

http://www.mdpi.com/2072-6651/3/9/1111/

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