VariantStore: an index for large-scale genomic variant search

Abstract Efficiently scaling genomic variant search indexes to thousands of samples is computationally challenging due to the presence of multiple coordinate systems to avoid reference biases. We present VariantStore, a system that indexes genomic variants from multiple samples using a variation gra...

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Bibliographic Details
Main Authors: Prashant Pandey, Yinjie Gao, Carl Kingsford
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Genome Biology
Subjects:
Online Access:https://doi.org/10.1186/s13059-021-02442-8