Brain Imaging of Nicotinic Receptors in Alzheimer's Disease

Neuronal nicotinic acetylcholine receptors (nAChRs) are a family of ligand-gated ion channels which are widely distributed in the human brain. Several lines of evidence suggest that two major subtypes (α4β2 and α7) of nAChRs play an important role in the pathophysiology of Alzheimer's disease (...

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Bibliographic Details
Main Authors: Jin Wu, Masatomo Ishikawa, Jichun Zhang, Kenji Hashimoto
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:International Journal of Alzheimer's Disease
Online Access:http://dx.doi.org/10.4061/2010/548913