Prediction and analysis of antibody amyloidogenesis from sequences.

Antibody amyloidogenesis is the aggregation of soluble proteins into amyloid fibrils that is one of major causes of the failures of humanized antibodies. The prediction and prevention of antibody amyloidogenesis are helpful for restoring and enhancing therapeutic effects. Due to a large number of po...

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Bibliographic Details
Main Authors: Chyn Liaw, Chun-Wei Tung, Shinn-Ying Ho
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3538782?pdf=render