The salivary scavenger and agglutinin (SALSA) binds MBL and regulates the lectin pathway of complement in solution and on surfaces

The salivary scavenger and agglutinin (SALSA) binds MBL and regulates the lectin pathway of complement in solution and on surfaces

The scavenger receptor cysteine-rich (SRCR) protein SALSA, also known as gp340, salivary agglutinin (SAG) and deleted in malignant brain tumor 1 (DMBT1), is a 340 kDa glycoprotein expressed on mucosal surfaces and secreted into several body fluids. SALSA binds to a broad variety of microbes and endo...

Full description

Bibliographic Details
Main Authors: Martin eParnov Reichhardt, Vuokko eLoimaranta, Steffen eThiel, Jukka eFinne, Seppo eMeri, Hanna eJarva
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-07-01
Series:Frontiers in Immunology
Subjects:
mucosal immunity
complement regulation
gp340
Lectin pathway
Mannan-binding lectin
salivary agglutinin
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00205/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00205/full

Similar Items