Carbon black nanoparticles promote endothelial activation and lipid accumulation in macrophages independently of intracellular ROS production.

Exposure to nanoparticles (NPs) may cause vascular effects including endothelial dysfunction and foam cell formation, with oxidative stress and inflammation as supposed central mechanisms. We investigated oxidative stress, endothelial dysfunction and lipid accumulation caused by nano-sized carbon bl...

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Bibliographic Details
Main Authors: Yi Cao, Martin Roursgaard, Pernille Høgh Danielsen, Peter Møller, Steffen Loft
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4153655?pdf=render