Immune Response to Therapeutic Staphylococcal Bacteriophages in Mammals: Kinetics of Induction, Immunogenic Structural Proteins, Natural and Induced Antibodies

Immune Response to Therapeutic Staphylococcal Bacteriophages in Mammals: Kinetics of Induction, Immunogenic Structural Proteins, Natural and Induced Antibodies

Bacteriophages are able to affect the human immune system. Phage-specific antibodies are considered as major factors shaping phage pharmacokinetics and bioavailability. So far, general knowledge of phage antigenicity nevertheless remains extremely limited. Here we present comparative studies of immu...

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Bibliographic Details
Main Authors: Zuzanna Kaźmierczak, Joanna Majewska, Paulina Miernikiewicz, Ryszard Międzybrodzki, Sylwia Nowak, Marek Harhala, Dorota Lecion, Weronika Kęska, Barbara Owczarek, Jarosław Ciekot, Marek Drab, Paweł Kędzierski, Marta Mazurkiewicz-Kania, Andrzej Górski, Krystyna Dąbrowska
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
bacteriophage
Staphylococcus aureus
antibodies
immune response
phage therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.639570/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.639570/full

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