Anticonvulsant activity of atorvastatin against seizure induced by pentylenetetrazole and maximal electroshock in mice
Statins are inhibitors of HMG-CoA reductase and inhibit cellular synthesis of cholesterol and isoprenoids. Studies have previously demonstrated the anti-inflammatory and vasoprotective effects of statins on cultured brain cells (astrocytes and microglia) and endothelial cells. Atorvastatin also prol...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Shiraz University of Medical Sciences
2015-03-01
|
| Series: | Trends in Pharmaceutical Sciences |
| Subjects: | |
| Online Access: | http://tips.sums.ac.ir/index.php/TiPS/article/view/20/18 |