Factors necessary to produce basoapical polarity in human glandular epithelium formed in conventional and high-throughput three-dimensional culture: example of the breast epithelium

<p>Abstract</p> <p>Background</p> <p>Basoapical polarity in epithelia is critical for proper tissue function, and control of proliferation and survival. Cell culture models that recapitulate epithelial tissue architecture are invaluable to unravel developmental and dise...

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Bibliographic Details
Main Authors: Sturgis Jennifer, Urazaev Albert, Wang Lei, Adissu Hibret A, Chaboub Lesley S, Plachot Cedric, Asem Elikplimi K, Lelièvre Sophie A
Format: Article
Language:English
Published: BMC 2009-11-01
Series:BMC Biology
Online Access:http://www.biomedcentral.com/1741-7007/7/77