A 3D epithelial–mesenchymal co-culture model of human bronchial tissue recapitulates multiple features of airway tissue remodeling by TGF-β1 treatment

A 3D epithelial–mesenchymal co-culture model of human bronchial tissue recapitulates multiple features of airway tissue remodeling by TGF-β1 treatment

Abstract Background The collagen gel contraction assay measures gel size to assess the contraction of cells embedded in collagen gel matrices. Using the assay with lung fibroblasts is useful in studying the lung tissue remodeling process in wound healing and disease development. However, the involve...

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Bibliographic Details
Main Authors: Shinkichi Ishikawa, Kanae Ishimori, Shigeaki Ito
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Respiratory Research
Subjects:
Bronchi
Transforming growth factor β1
Co-culture
Remodeling
Gel contraction
Online Access:http://link.springer.com/article/10.1186/s12931-017-0680-0

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http://link.springer.com/article/10.1186/s12931-017-0680-0

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