In silico approaches for predicting the half-life of natural and modified peptides in blood.

This paper describes a web server developed for designing therapeutic peptides with desired half-life in blood. In this study, we used 163 natural and 98 modified peptides whose half-life has been determined experimentally in mammalian blood, for developing in silico models. Firstly, models have bee...

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Bibliographic Details
Main Authors: Deepika Mathur, Sandeep Singh, Ayesha Mehta, Piyush Agrawal, Gajendra P S Raghava
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5983457?pdf=render