In Vivo Imaging of Molecular Clearance From Human Entorhinal Cortex: A Possible Method for Preclinical Testing of Dementia
Accumulation in the brain of metabolic waste products such as amyloid-β and hyperphosporylated tau (tau) is a hallmark of dementia (e.g., Alzheimer’s disease). One possible underlying mechanism is impaired cerebral paravascular (glymphatic) clearance of toxic solutes. Recently, we have provided evid...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2019-11-01
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Series: | Gerontology and Geriatric Medicine |
Online Access: | https://doi.org/10.1177/2333721419889739 |