In Vivo Imaging of Molecular Clearance From Human Entorhinal Cortex: A Possible Method for Preclinical Testing of Dementia

Accumulation in the brain of metabolic waste products such as amyloid-β and hyperphosporylated tau (tau) is a hallmark of dementia (e.g., Alzheimer’s disease). One possible underlying mechanism is impaired cerebral paravascular (glymphatic) clearance of toxic solutes. Recently, we have provided evid...

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Bibliographic Details
Main Authors: Per K. Eide MD, PhD, Geir Ringstad MD, PhD
Format: Article
Language:English
Published: SAGE Publishing 2019-11-01
Series:Gerontology and Geriatric Medicine
Online Access:https://doi.org/10.1177/2333721419889739