Aurora A site specific TACC3 phosphorylation regulates astral microtubule assembly by stabilizing γ-tubulin ring complex

Aurora A site specific TACC3 phosphorylation regulates astral microtubule assembly by stabilizing γ-tubulin ring complex

Abstract Background Astral microtubules emanating from the mitotic centrosomes play pivotal roles in defining cell division axis and tissue morphogenesis. Previous studies have demonstrated that human transforming acidic coiled-coil 3 (TACC3), the most conserved TACC family protein, regulates format...

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Bibliographic Details
Main Authors: Resmi Rajeev, Puja Singh, Ananya Asmita, Ushma Anand, Tapas K. Manna
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Molecular and Cell Biology
Subjects:
Centrosome
Microtubule
Mitosis
Protein phosphorylation
Mitotic spindle
Online Access:https://doi.org/10.1186/s12860-019-0242-z

Internet

https://doi.org/10.1186/s12860-019-0242-z

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