Wading pools and fading memories – place navigation in transgenic mouse models of Alzheimer’s disease

The Morris swim navigation task (‘water maze’) has been a primary research tools to assess hippocampal delpendent spatial learning and memory is rodents for three decades. Originally developed for rats, its application to mouse studies has been a tedious process, but nowadays there are more studies...

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Bibliographic Details
Main Author: Heikki eTanila
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-06-01
Series:Frontiers in Aging Neuroscience
Subjects:
tau
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2012.00011/full