The inhibitory effect of pyrroloquinoline quinone on the amyloid formation and cytotoxicity of truncated alpha-synuclein

<p>Abstract</p> <p>Background</p> <p>Parkinson's disease (PD) involves the selective damage of dopaminergic neuron cells resulting from the accumulation and fibril formation of alpha-synuclein. Recently, it has been shown that not only full-length alpha-synuclein,...

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Bibliographic Details
Main Authors: Kobayashi Natsuki, Kobayashi Masaki, Harada Ryuichi, Kim Jihoon, Sode Koji
Format: Article
Language:English
Published: BMC 2010-05-01
Series:Molecular Neurodegeneration
Online Access:http://www.molecularneurodegeneration.com/content/5/1/20