Targeting of reactive isolevuglandins in mitochondrial dysfunction and inflammation

Inflammation is a major cause of morbidity and mortality in Western societies. Despite use of multiple drugs, both chronic and acute inflammation still represent major health burdens. Inflammation produces highly reactive dicarbonyl lipid peroxidation products such as isolevuglandins which covalentl...

Full description

Bibliographic Details
Main Authors: Vladimir Mayorov, Peter Uchakin, Venkataraman Amarnath, Alexander V. Panov, Christy C. Bridges, Roman Uzhachenko, Bill Zackert, Christy S. Moore, Sean Davies, Anna Dikalova, Sergey Dikalov
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S221323171930480X