New Estrone Oxime Derivatives: Synthesis, Cytotoxic Evaluation and Docking Studies

The interest in the introduction of the oxime group in molecules aiming to improve their biological effects is increasing. This work aimed to develop new steroidal oximes of the estrane series with potential antitumor interest. For this, several oximes were synthesized by reaction of hydroxylamine w...

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Bibliographic Details
Main Authors: Catarina Canário, Mariana Matias, Vanessa Brito, Adriana O. Santos, Amílcar Falcão, Samuel Silvestre, Gilberto Alves
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/26/9/2687