beta-Glucocerebrosidase activity in murine epidermis: characterization and localization in relation to differentiation.

The intercellular lipids of the stratum corneum, which are highly enriched in ceramides, are critical for the mammalian epidermal permeability barrier. During the terminal stages of epidermal differentiation, the glucosylceramide content is dramatically reduced, while the content of free ceramides i...

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Bibliographic Details
Main Authors: WM Holleran, Y Takagi, G Imokawa, S Jackson, JM Lee, PM Elias
Format: Article
Language:English
Published: Elsevier 1992-08-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520407722