Expression of the longest RGS4 splice variant in the prefrontal cortex is associated with single nucleotide polymorphisms in schizophrenia patients

Expression of the longest RGS4 splice variant in the prefrontal cortex is associated with single nucleotide polymorphisms in schizophrenia patients

The Regulator of G protein signaling 4 (RGS4) gene is a candidate susceptibility gene for schizophrenia (SCZ). Previous studies showed that the mRNA level of the longest splice variant RGS4-1 was decreased in the dorsolateral prefrontal cortex (DLPFC) of SCZ patients compared with healthy controls....

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Bibliographic Details
Main Authors: Lan eDing, Miroslav eStyblo, Zuzana eDrobná, Ashok eHegde
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-02-01
Series:Frontiers in Psychiatry
Subjects:
Bipolar Disorder
psychiatric
Genotype
postmortem
allele
Regulatory region
Online Access:http://journal.frontiersin.org/Journal/10.3389/fpsyt.2016.00026/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fpsyt.2016.00026/full

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