Benificial effect of stachydrine on the traumatic brain injury induced neurodegeneration by attenuating the expressions of Akt/mTOR/PI3K and TLR4/NFκ-B pathway

Present investigation aims to explore the protective effect of stachydrine against traumatic brain injury (TBI) and also investigate the molecular mechanism of its action. TBI was induced by the fall a hammer (450 g) from the height of 1.5 m. and later stachydrine was administered for 2 weeks starti...

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Bibliographic Details
Main Authors: Yu Nianzu, Hu Si, Hao Zheng
Format: Article
Language:English
Published: De Gruyter 2018-12-01
Series:Translational Neuroscience
Subjects:
Online Access:https://doi.org/10.1515/tnsci-2018-0026