Characterization of Wnt/β-catenin and BMP/Smad signaling pathways in an in vitro model of amyotrophic lateral sclerosis

Characterization of Wnt/β-catenin and BMP/Smad signaling pathways in an in vitro model of amyotrophic lateral sclerosis

Different pathways activated by morphogens of the early embryonic development, such as the Wnt and the Bone Morphogenetic Protein (BMP) ligands, are involved in diverse physiological and pathological conditions of the nervous system, including neurodegeneration. In this work, we have analyzed the en...

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Bibliographic Details
Main Authors: Cristina ePinto, Pilar eCardenas, Nelson eOsses, Juan Pablo eHenríquez
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-12-01
Series:Frontiers in Cellular Neuroscience
Subjects:
beta Catenin
Motor Neurons
Smad Proteins
Wnt
ALS
BMP
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00239/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00239/full

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