PD-L1 expression and its effect on clinical outcomes of EGFR-mutant NSCLC patients treated with EGFR-TKIs

<b>Objective: </b> Epidermal growth factor receptor (EGFR) activation was reported to upregulate programmed death-ligand 1 (PD-L1) expression in lung cancer cells and subsequently contribute to immune escape, indicating its critical role in EGFR-driven lung tumors. This study characteriz...

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Bibliographic Details
Main Authors: Yuchen Bai, Xiaoxia Chen, Likun Hou, Jun Qian, Tao Jiang, Caicun Zhou, Maciej Ciebiada
Format: Article
Language:English
Published: China Anti-Cancer Association 2018-12-01
Series:Cancer Biology & Medicine
Subjects:
CD8
Online Access:http://www.cancerbiomed.org/index.php/cocr/article/view/1294