Complement-Dependent Mechanisms and Interventions in Periodontal Disease

Complement-Dependent Mechanisms and Interventions in Periodontal Disease

Periodontitis is a prevalent inflammatory disease that leads to the destruction of the tooth-supporting tissues. Current therapies are not effective for all patients and this oral disease continues to be a significant public health and economic burden. Central to periodontal disease pathogenesis is...

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Bibliographic Details
Main Authors: George Hajishengallis, Tetsuhiro Kajikawa, Evlambia Hajishengallis, Tomoki Maekawa, Edimara S. Reis, Dimitrios C. Mastellos, Despina Yancopoulou, Hatice Hasturk, John D. Lambris
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Immunology
Subjects:
complement
C3
therapeutics
compstatin Cp40
AMY-101
primate models
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00406/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00406/full

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