Modeling the Human Bone–Tumor Niche: Reducing and Replacing the Need for Animal Data
ABSTRACT Bone is the most common site for cancer metastasis. Understanding the interactions within the complex, heterogeneous bone–tumor microenvironment is essential for the development of new therapeutics. Various animal models of tumor‐induced bone disease are routinely used to provide valuable i...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2020-04-01
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Series: | JBMR Plus |
Subjects: | |
Online Access: | https://doi.org/10.1002/jbm4.10356 |