Human and Mouse TRPA1 Are Heat and Cold Sensors Differentially Tuned by Voltage

Transient receptor potential ankyrin 1 channel (TRPA1) serves as a key sensor for reactive electrophilic compounds across all species. Its sensitivity to temperature, however, differs among species, a variability that has been attributed to an evolutionary divergence. Mouse TRPA1 was implicated in n...

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Bibliographic Details
Main Authors: Viktor Sinica, Lucie Zimova, Kristyna Barvikova, Lucie Macikova, Ivan Barvik, Viktorie Vlachova
Format: Article
Language:English
Published: MDPI AG 2019-12-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/1/57