Analytical Sensitivity Comparison between Singleplex Real-Time PCR and a Multiplex PCR Platform for Detecting Respiratory Viruses.

Multiplex PCR methods are attractive to clinical laboratories wanting to broaden their detection of respiratory viral pathogens in clinical specimens. However, multiplexed assays must be well optimized to retain or improve upon the analytic sensitivity of their singleplex counterparts. In this exper...

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Bibliographic Details
Main Authors: Jayme Parker, Nisha Fowler, Mary Louise Walmsley, Terri Schmidt, Jason Scharrer, James Kowaleski, Teresa Grimes, Shanann Hoyos, Jack Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4646456?pdf=render