Multi-genome alignment for quality control and contamination screening of next-generation sequencing data.

The availability of massive amounts of DNA sequence data, from thousands of genomes even in a single project has had a huge impact on our understanding of biology, but also creates several problems for biologists carrying out those experiments. Bioinformatic analysis of sequence data is perhaps the...

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Bibliographic Details
Main Authors: James eHadfield, Matthew David Eldridge
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-02-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00031/full