Coordinated increase of γ-secretase reaction products in the plasma of some female Japanese sporadic Alzheimer's disease patients: quantitative analysis of p3-Alcα with a new ELISA system

Coordinated increase of γ-secretase reaction products in the plasma of some female Japanese sporadic Alzheimer's disease patients: quantitative analysis of p3-Alcα with a new ELISA system

<p>Abstract</p> <p>Background</p> <p>Aggregatable amyloid β-peptide (Aβ) and non-aggregatable p3-Alcα are metabolic products of the γ-secretase cleavage of amyloid β-protein precursor (APP) and Alcadeinα (Alcα), respectively. Familial AD (FAD) -linked mutations in the p...

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Main Authors: Konno Tomoko, Hata Saori, Hamada Yukiko, Horikoshi-Sakuraba Yuko, Nakaya Tadashi, Saito Yuhki, Yamamoto Tohru, Yamamoto Takayuki, Maeda Masahiro, Ikeuchi Takeshi, Gandy Sam, Akatsu Hiroyasu, Suzuki Toshiharu
Format: Article
Language:English
Published: BMC 2011-11-01
Series:Molecular Neurodegeneration
Online Access:http://www.molecularneurodegeneration.com/content/6/1/76

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http://www.molecularneurodegeneration.com/content/6/1/76

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