In vivo – in vitro toxicogenomic comparison of TCDD-elicited gene expression in Hepa1c1c7 mouse hepatoma cells and C57BL/6 hepatic tissue

<p>Abstract</p> <p>Background</p> <p><it>In vitro </it>systems have inherent limitations in their ability to model whole organism gene responses, which must be identified and appropriately considered when developing predictive biomarkers of <it>in vivo...

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Bibliographic Details
Main Authors: Boverhof Darrell R, Dere Edward, Burgoon Lyle D, Zacharewski Timothy R
Format: Article
Language:English
Published: BMC 2006-04-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/7/80