Human NANOS1 Represses Apoptosis by Downregulating Pro-Apoptotic Genes in the Male Germ Cell Line

Human NANOS1 Represses Apoptosis by Downregulating Pro-Apoptotic Genes in the Male Germ Cell Line

While two mouse NANOS paralogues, NANOS2 and NANOS3, are crucial for maintenance of germ cells by suppression of apoptosis, the mouse NANOS1 paralogue does not seem to regulate these processes. Previously, we described a human NANOS1 p.[(Pro34Thr);(Ser83del)] mutation associated with the absence of...

Full description

Bibliographic Details
Main Authors: Damian M. Janecki, Erkut Ilaslan, Maciej J. Smialek, Marcin P. Sajek, Maciej Kotecki, Barbara Ginter-Matuszewska, Patryk Krainski, Jadwiga Jaruzelska, Kamila Kusz-Zamelczyk
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
NANOS1
apoptosis
cell cycle
human infertility
NANOS1 mutation
Online Access:https://www.mdpi.com/1422-0067/21/8/3009

Internet

https://www.mdpi.com/1422-0067/21/8/3009

Similar Items