Minocycline as adjunctive treatment for treatment-resistant depression: study protocol for a double blind, placebo-controlled, randomized trial (MINDEP2)

Minocycline as adjunctive treatment for treatment-resistant depression: study protocol for a double blind, placebo-controlled, randomized trial (MINDEP2)

Abstract Background Available evidence suggests that adjunctive treatment with immunomodulatory medications may be effective in the treatment of major depressive disorder (MDD). A pilot trial of the tetracycline minocycline as adjunctive treatment in treatment-resistant depression (TRD), produced pr...

Full description

Bibliographic Details
Main Authors: Muhammad Ishrat Husain, Clare Cullen, Madeha Umer, Andre F. Carvalho, Stefan Kloiber, Jeffrey H. Meyer, Abigail Ortiz, Yuliya Knyahnytska, M. Omair Husain, Justine Giddens, Breno S. Diniz, Wei Wang, Allan H. Young, Benoit H. Mulsant, Zafiris J. Daskalakis
Format: Article
Language:English
Published: BMC 2020-04-01
Series:BMC Psychiatry
Subjects:
Depression
Minocycline
Inflammation
Anti-inflammatory
Clinical trial
Online Access:http://link.springer.com/article/10.1186/s12888-020-02553-9

Internet

http://link.springer.com/article/10.1186/s12888-020-02553-9

Similar Items