Tail-Anchored Protein Insertion by a Single Get1/2 Heterodimer

Tail-Anchored Protein Insertion by a Single Get1/2 Heterodimer

The Get1/2 transmembrane complex drives the insertion of tail-anchored (TA) proteins from the cytosolic chaperone Get3 into the endoplasmic reticulum membrane. Mechanistic insight into how Get1/2 coordinates this process is confounded by a lack of understanding of the basic architecture of the compl...

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Bibliographic Details
Main Authors: Benjamin E. Zalisko, Charlene Chan, Vladimir Denic, Ronald S. Rock, Robert J. Keenan
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Cell Reports
Subjects:
GET pathway
tail-anchored protein
membrane protein insertion
single-molecule FRET
proteoliposomes
molecular mechanism
Get1/2 transmembrane complex
biogenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717311427

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http://www.sciencedirect.com/science/article/pii/S2211124717311427

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