A plasmid-based Escherichia coli gene expression system with cell-to-cell variation below the extrinsic noise limit.

Experiments in synthetic biology and microbiology can benefit from protein expression systems with low cell-to-cell variability (noise) and expression levels precisely tunable across a useful dynamic range. Despite advances in understanding the molecular biology of microbial gene regulation, many ex...

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Bibliographic Details
Main Author: Zach Hensel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5662224?pdf=render