Deciphering Cell Lineage Specification during Male Sex Determination with Single-Cell RNA Sequencing

Deciphering Cell Lineage Specification during Male Sex Determination with Single-Cell RNA Sequencing

Summary: The gonad is a unique biological system for studying cell-fate decisions. However, major questions remain regarding the identity of somatic progenitor cells and the transcriptional events driving cell differentiation. Using time-series single-cell RNA sequencing on XY mouse gonads during se...

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Bibliographic Details
Main Authors: Isabelle Stévant, Yasmine Neirijnck, Christelle Borel, Jessica Escoffier, Lee B. Smith, Stylianos E. Antonarakis, Emmanouil T. Dermitzakis, Serge Nef
Format: Article
Language:English
Published: Elsevier 2018-02-01
Series:Cell Reports
Subjects:
single-cell RNA-seq
sex determination
testis
Sertoli cell
fetal Leydig cell
progenitors
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718300755

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http://www.sciencedirect.com/science/article/pii/S2211124718300755

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