A zebrafish transgenic model of Ewing’s sarcoma reveals conserved mediators of EWS-FLI1 tumorigenesis

SUMMARY Ewing’s sarcoma, a malignant bone tumor of children and young adults, is a member of the small-round-blue-cell tumor family. Ewing’s sarcoma family tumors (ESFTs), which include peripheral primitive neuroectodermal tumors (PNETs), are characterized by chromosomal translocations that generate...

Full description

Bibliographic Details
Main Authors: Stefanie W. Leacock, Audrey N. Basse, Garvin L. Chandler, Anne M. Kirk, Dinesh Rakheja, James F. Amatruda
Format: Article
Language:English
Published: The Company of Biologists 2012-01-01
Series:Disease Models & Mechanisms
Online Access:http://dmm.biologists.org/content/5/1/95