Murine Butyrophilin-like (Btnl) 1 and Btnl6 form heteromeric complexes in small intestinal epithelial cells and promote proliferation of local T lymphocytes

Murine Butyrophilin-like (Btnl) 1 and Btnl6 form heteromeric complexes in small intestinal epithelial cells and promote proliferation of local T lymphocytes

To date, few molecular conduits mediating the cross-talk between intestinal epithelial cells and intraepithelial lymphocytes (IELs) have been described. We recently showed that Butyrophilin-like (Btnl) 1 can attenuate the epithelial response to activated IELs, resulting in reduced production of pro-...

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Bibliographic Details
Main Authors: Cristina eLebrero-Fernández, Joakim Hans Bergström, Thaher ePelaseyed, Anna eBas-Forsberg
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-01-01
Series:Frontiers in Immunology
Subjects:
intestinal epithelial cells
mucosal immunity
Gamma Delta T cells
Intraepithelial lymphocytes
Butyrophilin-like (Btnl)
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00001/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00001/full

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