Molecular Mechanisms Underlying Protective Role of Quercetin on Copper Sulfate-Induced Nephrotoxicity in Mice

Copper overload is an established cause of nephrotoxicity, but the precise molecular mechanism remains unknown. Our study aimed to investigate the molecular mechanism of copper sulfate (CuSO4)-induced nephrotoxicity and the protective effect of the natural compound quercetin using a mouse model. Mic...

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Bibliographic Details
Main Authors: Xinyan Peng, Chongshan Dai, Min Zhang, Subhajit Das Gupta
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Veterinary Science
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2020.586033/full