Adherent cell remodeling on micropatterns is modulated by Piezo1 channels
Abstract Adherent cells utilize local environmental cues to make decisions on their growth and movement. We have previously shown that HEK293 cells grown on the fibronectin stripe patterns were elongated. Here we show that Piezo1 function is involved in cell spreading. Piezo1 expressing HEK cells pl...
Main Authors: | Deekshitha Jetta, Mohammad Reza Bahrani Fard, Frederick Sachs, Katie Munechika, Susan Z. Hua |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-03-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-021-84427-y |
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