Adherent cell remodeling on micropatterns is modulated by Piezo1 channels

Abstract Adherent cells utilize local environmental cues to make decisions on their growth and movement. We have previously shown that HEK293 cells grown on the fibronectin stripe patterns were elongated. Here we show that Piezo1 function is involved in cell spreading. Piezo1 expressing HEK cells pl...

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Bibliographic Details
Main Authors: Deekshitha Jetta, Mohammad Reza Bahrani Fard, Frederick Sachs, Katie Munechika, Susan Z. Hua
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-84427-y